Treatment with non-selective beta-blockers affects the systemic inflammatory response to bacterial DNA in patients with cirrhosis
نویسندگان
چکیده
منابع مشابه
Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis.
BACKGROUND Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown. METHODS We randomly assigned 213 patients with cirrhosis and portal hypertension (minimal hepatic venous pressure gradient [HVPG] of 6 mm Hg) to receive timolol, a nonselective beta-blocker (108 patients), or placebo (105 patients). T...
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چکیده ندارد.
15 صفحه اولSystemic inflammatory response syndrome in patients with liver cirrhosis.
BACKGROUND AND STUDY AIMS Patients with liver cirrhosis present an increased susceptibility to the systemic inflammatory response syndrome (SIRS), which is considered the cause of hospital admission in about 10% of patients and is present in about 40% of those admitted for ongoing complications. We tried to assess the prevalence of the SIRS with the possible effects on the course of the disease...
متن کاملNonselective Beta-blockers in Patients with Cirrhosis: "the Therapeutic Window".
For over 30 years, nonselective beta-blockers (NSBB) have been successfully used for preventing variceal bleeding in patients with cirrhosis and portal hypertension. Nevertheless, recent studies suggest that NSBB may be effective only within a particular "therapeutic window" in patients with advanced liver disease. Outside of this window, in early stages of cirrhosis and in very advanced cirrho...
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ژورنال
عنوان ژورنال: Liver International
سال: 2018
ISSN: 1478-3223
DOI: 10.1111/liv.13890